Our goal is to use fiber tractography, based on the anisotropic diffusion simulations, to improve and accommodate HARDI data technique. We can examine the white matter fibers that are connected to the brain using fiber tractography and anisotropic diffusion simulations. The fiber tracking schemes can examine the pathways of white matter tracts, quantify the white matter in the brain, and help identify white matter diseases (Multiple Sclerosis (MS), Alzheimer, stroke, chronic alcohol, Amyotrophic Lateral Sclerosis (ALS), and others). Since the efficiency of cognitive processing is highly dependent on the integrity of white matter pathways, fiber tractography is a novel technique in examining specific type of fibers that can potentially damage overall cognitive abilities.
Kang N, Zhang J, Carlson ES, Gembris D. White matter fiber tractography via anisotropic diffusion simulation in the human brain. IEEE Transactions on Medical Imaging, 24 (9): 1127-1137, 2005.